Understanding the Difference Between Tirzepatide (Mounjaro) and Semaglutide (Wegovy/Ozempic)

GLP-1 and GIP Analogues for Weight Loss:

Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro) are weekly injectable medications used for effective weight loss, especially when diet and exercise alone haven’t worked. These drugs mimic gut hormones — GLP-1 and GIP — which help regulate appetite, digestion, and blood sugar.

  • Semaglutide targets GLP-1 only, reducing hunger and slowing digestion, with around 15% average weight loss.

  • Tirzepatide targets both GLP-1 and GIP, offering stronger effects on appetite and metabolism, with up to 20%+ weight loss in trials.

Key Differences:

  • Tirzepatide offers more potent weight loss.

  • Both are weekly injections.

  • Side effects include nausea and digestive issues, with Tirzepatide potentially causing slightly more.

Niva Medical Clinic provides personalised, medically supervised weight loss programmes — unlike generic online services — with in-person assessments, GP monitoring, and lifestyle support. They serve patients across North West London and Hertfordshire.

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