Understanding the Difference Between Tirzepatide (Mounjaro) and Semaglutide (Wegovy/Ozempic)

GLP-1 and GIP Analogues for Weight Loss:

Semaglutide (Wegovy/Ozempic) and Tirzepatide (Mounjaro) are weekly injectable medications used for effective weight loss, especially when diet and exercise alone haven’t worked. These drugs mimic gut hormones — GLP-1 and GIP — which help regulate appetite, digestion, and blood sugar.

Semaglutide targets GLP-1 only, reducing hunger and slowing digestion, with around 15% average weight loss.
Tirzepatide targets both GLP-1 and GIP, offering stronger effects on appetite and metabolism, with up to 20%+ weight loss in trials.

Key Differences:

Tirzepatide offers more potent weight loss.
Both are weekly injections.
Side effects include nausea and digestive issues, with Tirzepatide potentially causing slightly more.

Niva Medical Clinic provides personalised, medically supervised weight loss programmes — unlike generic online services — with in-person assessments, GP monitoring, and lifestyle support. They serve patients across North West London and Hertfordshire.